Title

A prospective, multicenter, observational real-world study to evaluate the effectiveness of amlodipine on 24-hour blood pressure control using 24-hour ambulatory blood pressure monitoring, in adult patients with mild to moderate essential hypertension

Study design

Prospective, Multicenter, Observational, Real world study

Introduction

Hypertension (HTN) is an important public health problem in India and is ranked as the third most important risk factor for attributable burden of disease in south Asia.1 Various studies from India have reported a prevalence of 25% in urban population and 10% in rural population in India.2 Estimates by the WHO (2008) put HTN prevalence at 33.2% in men and 31.7% in women (overall prevalence 32.5%).3 Worldwide data in 2005 for the global burden of HTN reported that the projected rates for HTN by 2025 are 22.9% for men and 23.6% for women in India

The current definition of hypertension (HTN) is systolic blood pressure (SBP) values of 130mmHg or more and/or diastolic blood pressure (DBP) more than 80 mmHg. Hypertension has been among the most studied topics of the previous century and has been one of the most significant comorbidities contributing to the development of stroke, myocardial infarction, heart failure, and renal failure. Hypertension is a frequent, chronic, age-related disorder, which often entails debilitating cardiovascular and renal complications. Blood pressure is usually noted in combination with other cardiovascular risk factors.